Common clinical symptoms of anemia include:

Shortness of breath and fatigue are indeed common clinical symptoms of anemia. Anemia occurs when there is a deficiency of red blood cells or hemoglobin, which is responsible for transporting oxygen throughout the body. When oxygen delivery is compromised, the body's tissues and organs may not receive adequate oxygen, leading to feelings of fatigue and weakness. Additionally, the body may respond to low oxygen levels by increasing the respiratory rate, which can result in shortness of breath, especially during physical exertion.

In contrast, the other symptoms listed, while they may be associated with certain types of anemia, are not universally present in all cases. Splenomegaly can occur in some conditions related to hemolytic anemia, but it is not a common symptom across all anemias. Chills and fever tend to be related to infections or inflammatory processes rather than anemia itself. Jaundice can occur with hemolytic anemia or liver disease, but it is not a characteristic symptom of all forms of anemia, and enlarged lymph nodes do not typically relate directly to anemia. Understanding these associations helps clarify why shortness of breath and fatigue stand out as key symptoms of anemia.