What is the normal M:E ratio range in adults?

The normal myeloid to erythroid (M:E) ratio in adults typically ranges from 1.5:1 to 3.3:1. This ratio reflects the balance between myeloid cells, which are precursors of white blood cells, and erythroid cells, which are precursors of red blood cells, in the bone marrow. Maintaining this balance is essential for proper hematopoiesis, as disruptions could indicate underlying hematological disorders.

Elevated or decreased M:E ratios can suggest various conditions; for example, a lower ratio may indicate a response to anemia where erythropoiesis is increased, while an elevated ratio could indicate a myeloid lineage disorder. Understanding the normal range helps clinicians assess bone marrow function and diagnose potential disorders effectively.