Which cell stage is responsible for producing mature erythrocytes?

The cell stage responsible for producing mature erythrocytes is the orthchromic normoblast. During erythropoiesis, the development of red blood cells progresses through several stages, starting from the hematopoietic stem cells and advancing through various progenitor and precursor cells.

In the case of the orthchromic normoblast, this stage is characterized by a small cell size, dense nucleus, and the presence of a substantial amount of hemoglobin. As hemoglobin synthesis peaks in this stage, the cell prepares for enucleation, which is a crucial step in the formation of mature red blood cells. After the stage of the orthchromic normoblast, the cell undergoes the process of enucleation to become a reticulocyte and eventually matures into an erythrocyte.

This process highlights the significant role of the orthchromic normoblast in the pathway of erythrocyte formation, marking it as the final stage of mitotic activity before the transition to non-nucleated mature red blood cells.