Which component of the RBC membrane is primarily responsible for facilitating transport of molecules?

Glycophorin A plays a crucial role in the red blood cell (RBC) membrane by providing structural stability and facilitating transport. It is a type of transmembrane protein that extends across the membrane, providing a pathway for the transport of molecules. Glycophorin A is involved in the recognition of different blood groups and helps maintain the integrity of the cell membrane.

While cholesterol contributes to the fluidity and stability of the RBC membrane, it does not directly facilitate the transport of molecules. Cytoskeletal proteins provide support and maintain the shape of the RBC but are not primarily involved in transport functions. Phospholipids form the fundamental structure of the membrane and serve as a barrier to the passage of most molecules, thus not being involved in the active transport processes.

Glycophorin A's primary role as a transport facilitator, through its ability to interact with specific ligands and other proteins, underscores its importance in maintaining effective transport functions within the RBC membrane.