Which of the following is not related to the effects of erythropoietin?

Erythropoietin is a hormone primarily produced by the kidneys and plays a crucial role in the regulation of red blood cell production (erythropoiesis) in the bone marrow. It functions by stimulating erythroid progenitor cells to proliferate and differentiate into red blood cells.

The formation of pores in sinusoidal endothelial cells for marrow egress is not a direct effect of erythropoietin. While sinusoidal endothelial cells are involved in the egress of red blood cells from the marrow into the circulation, this process is more related to the structural changes and the regulation of vascular permeability within the bone marrow microenvironment rather than the action of erythropoietin itself.

On the other hand, erythropoietin influences the number of divisions of a normoblast by promoting the proliferation and differentiation of erythroid precursor cells, thereby increasing the output of red blood cells. It also affects the time between the mitotic divisions of normoblasts, leading to a more rapid advancement to the erythrocyte stage. Additionally, erythropoietin promotes the production of antiapoptotic molecules, which helps to prevent programmed cell death in erythroid progenitors, allowing for their survival and further development into mature red blood